- retrieves PubMed abstracts for your search query,
- detects terms from the Gene Ontology (GO) and Medical Subject Headings (MeSH) in the abstracts,
- displays the subset of the GO and MeSH relevant to the keywords, and
- allows you to browse the ontologies and display only papers containing specific GO and MeSH terms.
After performing a search, the resulting abstracts are annotated with your query keywords and GO and MeSH terms. The abstracts are grouped using the GO and MeSH terms, which appear in the text. Now the GO and MeSH hierarchies can be used to systematically explore the search results.
Note that only a subset of all GO and MeSH terms may be relevant to your query. This subset more frequent terms - is presented on the left hand side. Sorting documents to a highly organised network facilitates the finding of relevant documents significantly.
The hierarchy of content shows the whole GO and MeSH ontologies. GO and MeSH serve as table of contents in order to structure the over 16 million articles of the MEDLINE data base.
About Gene Ontology (GO)
The GO provides a controlled vocabulary to describe gene and gene products in different organisms. GO is a knowledge network containing about 20.000 biological terms. It is built up as a directed acyclic graph starting from three basic areas namely
- the molecular function of gene products,
- their role in multi-step biological processes, and
- their localization to cellular components.
GO terms are classified into only one of the three branches of the ontology. Although the ontology is presented as a tree, it is a network with cross links. So it is possible to navigate to a term of interest on different paths. Hence, a term of interest can be reached from quite different points of view.
About the Medical Subject Headings (MeSH)
MeSH is the controlled vocabulary thesaurus from National Library of Medicine's. It consists of sets of terms in a hierarchical structure that permits searching at various levels of specificity. At the most general level of the hierarchy are very broad headings such as "Anatomy" or "Diseases". More specific headings are found at more narrow levels.
There are more than 110,000 MeSH concepts in GoPubMed. There are also thousands of cross-references that assist in finding the most appropriate MeSH concept. So it is possible to navigate to a term of interest on different paths. Hence, a term of interest can be reached from quite different points of view. From the eleven levels of the MeSH hierarchy, GoPubMed uses the parts:
- Anatomy,
- Biological Sciences,
- Chemicals and Drugs,
- Diseases,
- Health Care,
- Natural Sciences,
- Organisms,
- Psychiatry and Psychology,
- Techniques and Equipment, and
- Technology, Industry, Agriculture
For further information, please visit:
http://www.gopubmed.com/