Variation is a cardinal feature of biology, the driver of diversity, and the engine of evolution, but it has a dark side. Alterations in DNA sequences and the resulting proteins that build our cells can sometimes lead to profound disruptions in physiologic function and cause disease.
The computer modelling tool will predict novel sites of binding for potential drugs that are more selective, leading to more effective drug targeting, increasing therapeutic efficacy and reducing side effects.
Wearable health devices, such as the popular Apple Watch, have changed the game, surfacing meaningful data that can paint a more complete picture of daily life and resulting health and disease for clinicians.
The COVID alert app is based on the Google-Apple exposure notification API (GAEN API), a functionality that the tech companies rolled out in April 2020. The Canadian government built an app around the GAEN API, which became the COVID alert app, and managed the system for uploading positive cases.